International Journal of Hepatology

Esophageal Varices: Pathophysiology, Approach and Clinical Dilemmas


Publishing date
20 Jul 2012
Status
Published
Submission deadline
02 Mar 2012

Lead Editor

1Division of Gastroenterology, McGill University, Montreal, QC, Canada

2Liver Unit, University of Montreal, Montreal, QC, Canada

3Liver Diseases Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, NIH, Bethesda, MD, USA


Esophageal Varices: Pathophysiology, Approach and Clinical Dilemmas

Description

Portal hypertension develops as a result of an increase in resistance or flow of portal blood through the liver vascular system. The increase in vascular resistance might be extrahepatic or intrahepatic in nature. Among all the causes, cirrhosis is the most common. This may lead to portal hypertension syndrome which includes esophageal varices, ascites, encephalopathy, and splenomegaly. The most clinically important complication of the above syndrome is the development of esophageal varices. Esophageal varices are associated with significant risk of upper gastrointestinal bleeding and high mortality.

We are in the process of inviting investigators to contribute original articles as well as review articles that will stimulate the continued effort to understand the pathophysiology behind the development of esophageal varices in cirrhotic and noncirrhotic patients. We would like to describe the spectrum of complications in adults and in the pediatric population, as well as the various treatment modalities and other important clinical issues which are associated with that phenomenon. Potential topics include, but are not limited to:

  • Recent understanding of the mechanism for esophageal varices development in cirrhotic patients
  • Clinical manifestations—complications
  • Noncirrhotic portal hypertension (acute and chronic portal vein thrombosis, Budd-Chiari syndrome, nodular regenerative hyperplasia, etc.) and the current approach
  • Medical approach: indication for screening, mode and frequency of screening, primary treatment, treatment of acute event, and secondary prevention
  • Endoscopy treatment
  • Other therapies: TIPS (indications, risk, complications), surgical
  • Anticoagulation in portal HTN
  • Pediatric manifestations of portal HTN

Articles published in this special issue will not be subject to the journal's Article Processing Charges.

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/ijhep/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 795063
  • - Editorial

Esophageal Varices: Pathophysiology, Approach, and Clinical Dilemmas

Nir Hilzenrat | Averell H. Sherker
  • Special Issue
  • - Volume 2012
  • - Article ID 879163
  • - Review Article

Etiology and Management of Hemorrhagic Complications of Portal Hypertension in Children

Alejandro Costaguta | Fernando Alvarez
  • Special Issue
  • - Volume 2012
  • - Article ID 203794
  • - Review Article

Clinical Manifestations of Portal Hypertension

Said A. Al-Busafi | Julia McNabb-Baltar | ... | Nir Hilzenrat
  • Special Issue
  • - Volume 2012
  • - Article ID 418369
  • - Review Article

Role of Self-Expandable Metal Stents in Acute Variceal Bleeding

Fuad Maufa | Firas H. Al-Kawas
  • Special Issue
  • - Volume 2012
  • - Article ID 167868
  • - Review Article

The Transjugular Intrahepatic Portosystemic Shunt in the Treatment of Portal Hypertension: Current Status

Gilles Pomier-Layrargues | Louis Bouchard | ... | Pierre Perreault
  • Special Issue
  • - Volume 2012
  • - Article ID 747095
  • - Review Article

Endoscopic Management of Portal Hypertension

Said A. Al-Busafi | Peter Ghali | ... | Marc Deschenes
  • Special Issue
  • - Volume 2012
  • - Article ID 672986
  • - Review Article

Management of Anticoagulation for Portal Vein Thrombosis in Individuals with Cirrhosis: A Systematic Review

Geneviève Huard | Marc Bilodeau
  • Special Issue
  • - Volume 2012
  • - Article ID 895787
  • - Review Article

Pathophysiology of Portal Hypertension and Esophageal Varices

Hitoshi Maruyama | Osamu Yokosuka
  • Special Issue
  • - Volume 2012
  • - Article ID 750150
  • - Review Article

Prevention and Management of Gastroesophageal Varices in Cirrhosis

Yen-I Chen | Peter Ghali
  • Special Issue
  • - Volume 2012
  • - Article ID 343591
  • - Review Article

Towards Noninvasive Detection of Oesophageal Varices

Kara Rye | Robert Scott | ... | Jan Freeman
International Journal of Hepatology
 Journal metrics
Acceptance rate-
Submission to final decision70 days
Acceptance to publication35 days
CiteScore2.280
Impact Factor-
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