Clinical Study

Increased Nitric Oxide and Attenuated Diastolic Blood Pressure Variability in African Americans with Mildly Impaired Renal Function

Table 3

Univariate regression analyses predicting GFR.

VariableβP Value

Age (years)−0.276NS
Male Gender0.005NS
Med. Taper−0.282NS
BMI (kg/m2)0.179NS
Fat Free Mass (kg)0.091NS
Fat Mass (kg)0.124NS
Total Cholesterol (mg/dL)−0.306NS
LDL Cholesterol (mg/dL)−0.152NS
HDL Cholesterol (mg/dL)−0.185NS
Triglycerides (mg/dL)−0.252NS
Glucose (mg/dL)0.068NS
Awake SBP (mmHg)−0.038NS
Sleep SBP (mmHg)−0.005NS
24-hr SBP (mmHg)0.023NS
Awake DBP (mmHg)0.131NS
Sleep DBP (mmHg)0.154NS
24-hr DBP (mmHg)0.213NS
Awake MAP (mmHg)0.052NS
Sleep MAP (mmHg)0.120NS
24-hr MAP (mmHg)0.145NS
Awake Systolic BPV (mmHg)0.133NS
Sleep Systolic BPV (mmHg)0.169NS
24-hr Systolic BPV (mmHg)0.199NS
Awake Rate of SBP Variation (mmHg/min)0.114NS
Sleep Rate of SBP Variation (mmHg/min)0.135NS
24-hr Rate of SBP Variation (mmHg/min)0.153NS
Awake Diastolic BPV (mmHg)0.549<.001
Sleep Diastolic BPV (mmHg)0.240NS
24-hr Diastolic BPV (mmHg)0.524.001
Awake Rate of DBP Variation (mmHg/min)0.573<.001
Sleep Rate of DBP Variation (mmHg/min)0.228NS
24-hr Rate of DBP Variation (mmHg/min)0.626<.001
Awake MAPV (mmHg)0.357.033
Sleep MAPV (mmHg)0.164NS
24-hr MAPV (mmHg)0.431.008
Awake Rate of MAP Variation (mmHg/min)0.342.041
Sleep Rate of MAP Variation (mmHg/min)0.163NS
24-hr Rate of MAP Variation (mmHg/min)0.383.014

BMI, body mass index; BPV, blood pressure variability; DBP, diastolic blood pressure; GFR, glomerular filtration rate; HDL, high-density lipoprotein; LDL, low-density lipoprotein; MAP, mean arterial pressure, MAPV, mean arterial pressure variability; NS, nonsignificant; SBP, systolic blood pressure.