Promoter Polymorphism of RGS2 Gene Is Associated with Change of Blood Pressure in Subjects with Antihypertensive Treatment: The Azelnidipine and Temocapril in Hypertensive Patients with Type 2 Diabetes Study

Table 3

Genotype frequencies of 22 SNPs.

SNP Name	Major Homo (𝑛)		Hetero (𝑛)		Minor Homo (𝑛)		Hardy-Weinberg Expectation(o value)
ACE Ins/Del (I/D)	II	15	ID	23	DD	6	0.54
ADD1 Gly460Trp (G/T)	GG	10	GT	24	TT	10	0.55
ADIPOQ Ile164Thr (T/C)	TT	44	TC	0	CC	0	-
ADRB1 Ser49Gly (G/A)	GG	1	GA	6	AA	37	0.24
ADRB1 Arg389Gly (G/C)	GG	3	GC	14	CC	27	0.53
ADRB2 Gly16Arg (A/G)	AA	14	AG	18	GG	12	0.23
ADRB2 Glu27Gln (C/G)	CC	41	CG	3	GG	0	0.81
ADRB3 Trp64Arg (T/C)	TT	29	TC	13	CC	2	0.73
AGT Met235Trp (T/C)	TT	31	TC	12	CC	1	0.90
AGTR1 A1166C (A/C)	AA	36	AC	7	CC	1	0.38
ALDH2 Glu487Lys (G/A)	GG	29	GA	13	AA	2	0.73
ARHGAP8 Arg338Gly (C/G)	CC	9	CG	20	GG	15	0.63
BDKRB2 T-58C (T/C)	TT	7	TC	23	CC	14	0.63
FASL G-670A (G/A)	GG	16	GA	17	AA	11	0.15
GRK4 Ala486Val (C/T)	CC	12	CT	20	TT	12	0.55
GRK4 Arg65Leu (G/T)	GG	33	GT	9	TT	2	0.21
hOGG1 Ser326Cys (G/C)	GG	7	GC	24	CC	13	0.46
MTHFR C677T (C/T)	CC	16	CT	24	TT	4	0.24
RGS2 A to G in promoter (A/G)	AA	9	AG	22	GG	13	0.96
RGS2 A-638G (A/G)	AA	9	AG	23	GG	12	0.74
SLC12A3 Arg904Gln (G/A)	GG	39	GA	5	AA	0	0.69
TGFB1 Leu10Pro (T/C)	TT	12	TC	24	CC	8	0.51