Genetic Determinants of Osteoporosis: Common Bases to Cardiovascular Diseases?

Table 3

QTLs identified and replicated in genome-wide linkage studies for osteoporosis [145]. Asterisks indicate genetic region associated also to clinical CVD events through genome-wide association studies [147].

QTLs replicated in at least two studies	QTLs replicated in at least three studies	QTLs replicated in at least five studies
- 2p21-24	- 13q31-34	- 1p36
- 2q33-37*	- 17p11-13	- 1q21-24
- 3q12-26		- 4q31-34
- 4p15-16		- 12q23-24*
- 5q33-35
- 6p21
- 8q24-qter
- 10q26
- 11q23-24
- 14q12-24
- 14q31-32
- 16p13
- 19p13-q13
- 21q22-qter*