Clinical Study

Improving Blood Pressure Control in Patients with Diabetes Mellitus and High Cardiovascular Risk

Table 2

Rates (per 100 patient years) for individual end-points.

End-pointWithout diabetesWith diabetes -value
NifedipinePlaceboHazard ratio (95% C. I.)NifedipinePlaceboHazard ratio (95% C. I.)

All-cause death1.531.431.07 (0.89, 1.28)2.272.151.05 (0.74, 1.51).942
Myocardial Infarction1.361.251.09 (0.9, 1.32)2.022.280.89 (0.61, 1.29).326
Heart Failure0.370.510.72 (0.52, 1.01)1.011.520.67 (0.41, 1.49).771
Stroke0.330.490.67 (0.47, 0.94)0.90.731.22 (0.67, 2.23).086
Coronary Artery Bypass Grafting1.461.920.76 (0.64, 0.9)2.612.920.9 (0.64, 1.25).395
Percutaneous Coronary Intervention2.082.210.94 (0.81, 1.1)2.573.110.83 (0.59, 1.15).482
Peripheral Revascularisation0.720.561.27 (0.96, 1.67)1.211.051.16 (0.7, 1.94).749
Refractory Angina0.760.860.89 (0.7, 1.14)1.091.500.73 (0.45, 1.18).47
Coronary Angiography5.226.290.83 (0.75, 0.92)6.939.280.75 (0.61, 0.93).384

-value for diabetes status/treatment interaction term.