The Relationship between the Transforming Growth Factor 𝛽1 T29C Gene Polymorphism and Left Ventricular Geometry and Function in Hypertensive Subjects

Table 4

Left ventricular geometry and function in hypertensives with left ventricular hypertrophy subgrouped according to Leu¹⁰→Pro¹⁰ TGF𝛽1 genotypes.

	TT n. 30	TC n. 128	CC n. 40
LVIDd (mm)	49 ± 3	48 ± 4	48 ± 5
IVSTd (mm)	11 ± 1	11.9 ± 2	11,8 ± 2
PWTd (mm)	9.6 ± 1	10.5 ± 2	10.6 ± 1
RWT	0.39 ± 0.1	0.44 ± 0.1	0.44 ± 0.1
LVM (gr)	197 ± 33	228 ± 40*	216 ± 55*
LVM/h^2.7 (gr/h^2.7)	53 ± 8	59 ± 10*	56 ± 9*
EF %	63 ± 3	57 ± 2*	56 ± 3*
E/A	1.5 ± 0.4	1.4 ± 0.3	1.4 ± 0.4
DTE (ms)	202 ± 38	204 ± 42	205 ± 44
IVRT (ms)	80 ± 12	78 ± 15	81 ± 14

LVIDd: Left ventricular telediastolic internal diameter; IVSTd: Interventricular septum thickness; PWTd: Posterior wall thickness; LVM: Left ventricular mass; LVM/h^2.7: Left ventricular mass indexed 2.7; RWT: Relative wall thickness; EF: Ejection fraction; E/A: Peak early transmitral flow/peak late transmitral flow; DTE: E deceleration time; IVRT: Isovolumic relaxation time.
* 𝑃<.05 versus TT.