Genome-Wide Association Study of Coronary Artery Disease

Table 3

Representatives of chip-based GWAS of CAD/MI.

Author, year	Phenotype	No. of cases/controls	Chromosomal loci	OR
Helgadottir et al. [24]	MI	4587/12767	9p21	1.28
McPherson et al. [27]	CAD	3505/18745	9p21	1.26 (CCHS study)
			9p21	1.16 (CCHS study)
WTCCC [31]	CAD	2000/3000	9p21.3	1.47
Samani et al. [32]	CAD	2801/4582	9p21.3	1.28 (adjusted German)
			6q25.1	1.23 (adjusted German)
			2q36.3	1.08 (adjusted German)
			1p13.3	1.29
			1q41	1.2
			10q11.21	1.33
			15q22.33	1.21
CAD Consortium, [33]	CAD	11550/11205	9p21	1.2
			1p13.3	1.13
			1p41	1.1
			10q11.21	1.11
Clarke et al. [59]	CAD	7991/7946	6q26-27	1.51