Research Article

The Relationship between Natriuretic Peptide Precursor a Gene T2238C Polymorphism and Hypertension: A Meta-Analysis

Table 1

The baseline characteristics of all qualified studies in this meta-analysis.

Author, ref and yearCountry (Ethnicity)DesignStatusAge, yearGender, M (%)BMI, kg/m2SBP, mmHgDBP, mmHgT2238C
TTTCCC

Rahmutula et al. [8]
2001
Japan (Japanese)H-BCases50 (8)65.6724.7 (3.7)170 (20)105 (12)222110
Controls49 (10)69.9523 (3.1)115 (13)70 (10)200130

Nannipier et al. [7]
2001
Europe (White)P-BCases56 (11)47.9325.9 (2.8)141 (15)86 (10)95260
Controls41 (10)47.6224.4 (3.2)122 (14)78 (8)67371

Rutledge et al. [6]
1995
US (Black)H-BCases44.7 (15.2)56.70—*17367
Controls44.8 (14.7)65.9019169

Hu et al. [9]
2010
China (Han Chinese)H-BCases57.71 (9.97)4823.79 (2.99)171.47 (13.01)100.74 (8.34)9730
Controls55.05 (10.64)43.3024.24 (4.50)115.66 (10.99)73.49 (8.15)9340

Tian and Cheng [10]
2010
China (Han Chinese)H-BCases59.89 (9.81)72.0024.33 (3.69)170.95 (23.86)105.67 (14.35)960142
Controls59.68 (9.78)70.0023.31 (3.21)115.59 (20.85)70.20 (11.00)962122

Li et al. [11]
2005
China (Kazakh Chinese)P-BCases46.80 (7.82)40.8926.27 (4.84)168.53 (24.72)104.51 (15.02)273355
Controls45.75 (8.63)45.3725.16 (5.63)117.39 (11.36)73.95 (8.58)20518716

Wang and Mao [12]
2009
China (Han Chinese)H-BCases68.61 (12.76)57.14220180
Controls68.45 (13.19)59.2717950

Ref: reference number; P-B: population-based design; H-B: hospital-based design; M (%): male (percent); BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure. *Information not available. Data are expressed as mean (SD) unless otherwise indicated.