International Journal of Hypertension

Research Article

Evaluation of Transforming Growth Factor Beta-1 Gene 869T/C Polymorphism with Hypertension: A Meta-Analysis

Table 1

The baseline characteristics of all qualified studies in this meta-analysis.


Author and Ref.	Ethnicity	Design	Status	Number	869C (%)	Age, years	Males (%)	BMI, kg/m²	SBP, mmHg	DBP, mmHg	TG, mmol/L	TC, mmol/L	HDLC, mmol/L	LDLC, mmol/L	Glucose, mmol/L

Yamada et al. [11]	Japan	P-B	Cases Controls	754 1477	46.75% 44.62%	56.62^†	49.83^†	22.73^†	121.05^†	74.33^†	1.34^†	5.66^†	1.54^†	—* —	5.64^†
Wei et al. [19]	Zhuang	H-B	Cases	172	55.23%	62.7	59.88	26.1	162.9	98.6	1.81	5.09	1.27	3.02	5.47
Wei et al. [19]	Zhuang	H-B	Controls	180	44.72%	60.3	58.33	23.9	125.4	78.6	1.79	4.38	1.32	2.88	5.4
Hu et al. [20]	Han	H-B	Cases	396	49.37%	56.5	69.44	25.6	157.3	96.6	1.97	—	—	—	—
Hu et al. [20]	Han	H-B	Controls	214	49.30%	56.2	68.22	23.9	119.5	78.6	1.54	—	—	—	—
Zhang et al. [21]	Han	H-B	Cases	186	54.03%	71.9	55.38	28.7	150.9	93.6	1.4	4.5	1.1	3.2	5.3
Zhang et al. [21]	Han	H-B	Controls	105	46.67%	—	—	25.7	128.1	83.1	1.4	4.3	1.1	3.1	5.2
Wei et al. [22]	Han	H-B	Cases	120	57.50%	63.2	60.00	26.3	162.1	97.9	1.81	5.12	1.29	3.01	5.45
Wei et al. [22]	Han	H-B	Controls	130	45.38%	60.5	59.23	23.7	119.4	78.9	1.79	4.34	1.31	2.98	5.4
Panoulas et al. [12]	White^‡	H-B	Cases	268	34.70%	—	—	27.8^†	—	—	1.18^†	5.47^†	1.63^†	—	—
Panoulas et al. [12]	White^‡	H-B	Controls	401	36.66%	50.41	60.3%	27.8^†	—	—	1.18^†	5.47^†	1.63^†	—	—
Zhang et al. [23]	Han	H-B	Cases	99	53.54%	—	—	—	—	—	—	—	—	—	—
Zhang et al. [23]	Han	H-B	Controls	49	41.84%	—	—	—	—	—	—	—	—	—	—
He et al. [10]	Kazakh	P-B	Cases	365	62.19%	48.46	46.85	27.45	153.57	99.42	1.38	5.01	1.46	3.2	5.97
He et al. [10]	Kazakh	P-B	Controls	435	50.69%	46.96	44.14	24.21	114.24	75.68	0.93	4.57	1.47	2.92	5.63
He et al. [10]	Han	P-B	Cases	387	61.11%	49.33	46.25	26.22	147.86	93.84	1.67	4.75	1.44	3.15	5.81
He et al. [10]	Han	P-B	Controls	413	51.21%	48.89	45.52	24.32	114.21	77.75	1.27	4.41	1.41	2.81	5.72

Ref., reference; P-B, population based; H-B, hospital based; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; TG, triglyceride; TC, total cholesterol; HDLC, high-density lipoprotein cholesterol; LDLC, low-density lipoprotein cholesterol. Data are expressed as mean values unless otherwise indicated. *Not available. ^†Information was obtained from the whole population. ^‡Fraction of Whites is 96.8%.