Clinical Study

Consumption of High-Polyphenol Dark Chocolate Improves Endothelial Function in Individuals with Stage 1 Hypertension and Excess Body Weight

Table 3

Metabolic variables and biomarkers of inflammation and oxidative stress at baseline (week 0) and at the end of the study (week 4).

VariableWeek 0 
( )
Week 4 
( )

Glucose (mg/dL)90.60 ± 2.6088.65 ± 2.750.55
Insulin ( U/mL) 21.86 ± 3.1123.49 ± 2.940.19
HOMA-IR4.94 ± 0.795.08 ± 0.630.20
Total cholesterol (mg/dL)199.00 ± 7.41195.15 ± 9.250.55
HDL cholesterol (mg/dL)50.85 ± 2.3148.75 ± 2.640.43
LDL cholesterol (mg/dL)122.15 ± 6.71122.00 ± 9.240.98
Triglycerides (mg/dL)132.80 ± 11.18122.55 ± 11.770.29
High sensitive CRP (mg/dL)0.93 ± 0.27 0.61 ± 0.120.24
Tumor necrosis factor- (pg/mL)17.51 ± 8.0318.96 ± 9.020.18
Interleucine-6 (pg/mL)87.87 ± 20.669.40 ± 14.70.17
Oxidized LDL ( g/mL)0.11 ± 0.010.12 ± 0.010.60

Values are expressed as mean ± standard error.
HDL: high-density lipoprotein, LDL: low density lipoprotein, CRP: C-reactive protein.