International Journal of Hypertension / 2012 / Article / Fig 3

Clinical Study

Role of HO/CO in the Control of Peripheral Circulation in Humans

Figure 3

Effect of heme oxygenase inhibition with stannous mesoporphyrin IX (SnMP) (200 μM) and nitric oxide synthase inhibition with L-NG-Nitroarginine methyl ester (L-NAME) (100 μM) on vasodilatation induced by acethylcholine (ACh) in skin circulation evaluated by laser Doppler flowmetry. ACh, SnMP, and L-NAME were locally administered by iontophoresis. *P versus baseline; **P versus Ach.

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