Evaluation of Clinical Variables Associated with Increased Carotid Intima-Media Thickness in Middle-Aged Hypertensive Women

Table 1

Clinical, anthropometric and biochemical characteristics of both groups.

Parameter	IMT ≤ 0.9; (𝑛=76)	IMT > 0.9; (𝑛=40)	𝑃-value
Age, years	50.8±6.6	53.5±7.1^∗	0.044
BMI, kg/m^2	28.9±4.5	29.5±4.9	0.471
Waist, cm	98.4±11.2	99.1±11.1	0.733
Systolic BP, mmHg	135±16	143±21^∗	0.020
Diastolic BP, mmHg	85±11	83±9	0.253
Pulse pressure, mmHg	49±11	60±17^∗∗∗	<0.001
Metabolic Syndrome, n(%)	49(64.5)	33(82.5)*	0.043
eGFR, mL/min	75±14	74±15	0.863
Glucose, mg/dL	88±19	87±14	0.735
Creatinine, mg/dL	0.80±0.13	0.81±0.13	0.740
Total cholesterol, mg/dL	209±54	255±64	0.157
HDL-cholesterol, mg/dL	49±8	44±7^∗∗	0.004
LDL-cholesterol, mg/dL	130±50	149±57	0.070
Triglycerides, mg/dL	144±84	150±71	0.731
hsCRP, mg/L	2.31±1.21	3.05±1.34^∗	0.016
IMT, mm	0.74±0.09	1.03±0.10 ***	<0.001

Data expressed as mean ± SD or 𝑛(%) when indicated; IMT: intima-media thickness; BMI: body mass index; BP: blood pressure; eGFR: estimated glomerular filtration rate; HDL: high density lipoprotein; LDL: low density lipoprotein; hsCRP: high-sensitive C-reactive protein; ACE: angiotensin converting enzyme; ARB: angiotensin receptor blocker. ^∗𝑃<0.05, ^∗∗𝑃<0.01^∗∗∗,𝑃<0.001.