Clinical Study

Cognitive Functions and Cognitive Reserve in Relation to Blood Pressure Components in a Population-Based Cohort Aged 53 to 94 Years

Table 3

Cognitive tests scores by blood pressure value adjusted for age and education.

Tests Whole cohort ( ) Normotensive subjects ( ) Hypertensives subjects ( ) value crude value adjusted for age and education

Mini-mental state examination
(25.8–26.6)

(27.0–28.3)

(25.4–26.4)
<0.005 <0.05
Digit span
(5.7–6.0)

(5.8–6.5)

(5.6–5.9)
0.04 0.3 (NS)
Immediate prose memory
(7.8–9.0)

(8.2–11.2)

(7.4–8.7)
0.03 0.7 (NS)
Delayed prose memory
(9.9–11.3)

(11.0–14.3)

(9.4–10.9)
<0.01 0.9 (NS)
Memory with interference at 10 sec
(3.6–4.3)

(4.6–6.3)

(3.2–4.0)
<0.0001 <0.05
Memory with interference at 30 sec
(0.9–1.5)

(1.4–3.2)

(0.7–1.3)
<0.005 0.2 (NS)
Trail making test A
(71.8–82.1)

(59.8–83.4)

(72.7–84.2)
0.3 (NS) 0.6 (NS)
Trail making test B
(144.8–171.5)

(109.3–152.0)

(153.1–185.7)
<0.01 0.2 (NS)
Phonemic verbal fluency
(7.5–8.4)

(8.2–9.9)

(7.2–8.3)
0.030.9 (NS)
Overlapping figure
(15.6–17.6)

(18.0–22.3)

(14.7–16.9)
<0.001 0.2 (NS)
Clock drawing test
(6.0–6.8)

(7.6–9.0)

(5.5–6.5)
<0.0001 <0.01
Cognitive reserve index
(92.5–96.4)

(95.9–102.7)

(91.2–95.7)
0.03 <0.05

95% confidence intervals in brackets; NS: nonsignificant difference.