The Prorenin and (Pro)renin Receptor: New Players in the Brain Renin-Angiotensin System?

Figure 1

(Pro)renin receptor expression in the C57Bl/6J mouse brain. Triple immunofluorescence staining for PRR (red), neuron-specific nuclear protein (green, neuron marker), and glial fibrillary acidic protein (blue, astroglia marker) revealed that PRR is expressed in both neurons and astroglia with prominent expression in the neurons. Arrows indicate the colocalization of PRR with neurons or astroglia.