Influence of Angiotensin II Subtype 2 Receptor (R) Antagonist, PD123319, on Cardiovascular Remodelling of Aged Spontaneously Hypertensive Rats during Chronic Angiotensin II Subtype 1 Receptor (R) Blockade
Figure 6
Media to lumen ratio of (a) aortic and (b) intramyocardial vessels of adult SHRs treated with vehicle (control, ), candesartan cilexetil (2 mg/kg/day) alone () or in combination with PD123319 (10 mg/kg/day, ) or PD123319 alone (). Media to lumen ratio of (c) aortic and (d) intramyocardial vessels of senescent SHRs treated with vehicle (control, ), candesartan cilexetil alone () or in combination with PD123319 (), PD123319 alone (), or hydralazine (30 mg/kg/day, ). * versus control (1-way ANOVA).
