Apo A1 Mimetic Rescues the Diabetic Phenotype of HO-2 Knockout Mice via an Increase in HO-1 Adiponectin and LKBI Signaling Pathway
Effect of L-4F on blood glucose, blood pressure, insulin sensitivity, and glucose tolerance in HO-2 null mice. (a) Blood glucose. Values are means ± SE, versus WT; # versus HO-2(−/−). (b) Blood pressure values are means ± SE, versus respective WT, # versus respective HO-2(−/−). HO-2(−/−). (c) Intraperitoneal insulin sensitivity (IPITT) and glucose tolerance (IPGTT) (d) tests were performed as described in research designs and methods. Results are means ± SE, . (IPITT) * versus WT, # versus HO-2(−/−), (IPGTT). * versus WT, # versus HO-2(−/−).
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