International Journal of Hypertension / 2012 / Article / Fig 4

Research Article

Reciprocal Effects of Oxidative Stress on Heme Oxygenase Expression and Activity Contributes to Reno-Vascular Abnormalities in EC-SOD Knockout Mice

Figure 4

(a) EETs levels in WT and EC-SOD(−/−) mice and mice treated with CoPP. EETs levels were determined as described in Methods. Results are mean ± SE, ; * versus WT mice, versus EC-SOD(−/−) and + versus WT + CoPP mice. (b) Adiponectin levels in WT and EC-SOD(−/−) mice and mice treated with CoPP. Adiponectin levels were determined as described in methods. Results are mean ± SE, ; * versus WT mice, versus EC-SOD(−/−) mice, and + versus WT + CoPP mice. (c) AKT and pAKT proteins in arteries of WT and EC-SOD(−/−) mice. Mice were injected with CoPP once a week as described in Methods. Blots are representative of four separate experiments. Results are expressed as mean ± SE, * versus WT, versus EC-SOD(−/−), + versus WT + CoPP mice.
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740203.fig.004b
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