Deficiency of ACE2 in Bone-Marrow-Derived Cells Increases Expression of TNF-α in Adipose Stromal Cells and Augments Glucose Intolerance in Obese C57BL/6 Mice

Table 1

Characteristics of chimeric HF-fed mice transplanted with Ace2^+/y or ^−/y bone marrow.

	𝐴𝑐𝑒2^+/𝑦	𝐴𝑐𝑒2^−/𝑦
Body weight (g)	45±1	46±1
Body fat by DEXA (%)	40±1	39±1
Serum cholesterol (mg/dL)	227±9	240±12
Serum triglycerides (mg/dL)	91±9	77±8
Serum NEFAs (mEq/L)	4.3±0.3	4.2±0.4
Plasma renin (ng/mL)	8±1	5±1
Plasma AngII (pg/mL)	243±50	154±35
Serum ACE activity (nmol/mL/min)	742±77	686±96

Data are mean ± SEM from 𝑁=3–11 mice/donor genotype.