Multilocus Family-Based Association Analysis of Seven Candidate Polymorphisms with Essential Hypertension in an African-Derived Semi-Isolated Brazilian Population

Table 7

Best predictive models from GMDR analyses.

Model	Test accuracy	CVC	P value
	Hypertension
GNB3(G-350A), GRK4	0.4884	4	0.5324
NOS3, GNB3(C825t), ADD2	0.5569	4	0.0792
GNB3(C825t), GNB3(G-350A), AGT, GRK4	0.5850	3	0.0222
	Systolic blood pressure
GNB3(G-350A), GRK4	0.5220	5	0.2644
NOS3, GNB3 (G-350A), AGT	0.5752	5	0.0444
ACE, GNB3(G-350A), ADD2, GRK4	0.5282	4	0.2440
	Diastolic blood pressure
NOS3, GRK4	0.6031	9	0.0044
ACE, ADD2, GRK4	0.5677	3	0.0724
ACE, NOS3, GNB3(C825t), GRK4	0.6347	6	0.0014

CVC: cross-validation consistency.