Cardiac-Autonomic Imbalance and Baroreflex Dysfunction in the Renovascular Angiotensin-Dependent Hypertensive Mouse

Figure 1

The procedure used to induce angiotensin-dependent hypertension in the mouse. A solid, stainless steel clip with an opening width of 0.12 mm (a) is placed around the left renal artery to cause stenosis (b), which results in the atrophy of the clipped kidney and hypertrophy of the contralateral, nonclipped kidney (c) and hypertension.