The Brain Renin-Angiotensin System and Mitochondrial Function: Influence on Blood Pressure and Baroreflex in Transgenic Rat Strains

<table>Proposed model: Ang-(1–7) through indirect (NADPH oxidase-mediated ROS) and/or direct interactions with mitochondria can attenuate ROS in dorsal medulla resulting in reduced blood pressure and enhanced baroreflex and mitochondrial function. ROS: reactive oxygen species; MAP: mean arterial pressure; BRS: baroreflex sensitivity; MF: Mitochondrial function; ?: not known.</table>

International Journal of Hypertension

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Figure 1: The Brain Renin-Angiotensin System and Mitochondrial Function: Influence on Blood Pressure and Baroreflex in Transgenic Rat Strains 