Research Article
Low Diastolic Blood Pressure as a Risk for All-Cause Mortality in VA Patients
Table 1
Characteristics of patients, according to diastolic blood pressure before matching*.
| | Characteristic | Patients with DBP <70
() | Patients with DBP ≥70
() | P value |
| | Age (yr) | 70.7 ± 9.6 | 64.6 ± 9.5 | <0.001 | | Comorbidities | | | | | Hypertension | 4275 (69.2) | 5243 (64.8) | <0.001 | | Diabetes | 2201 (35.6) | 2006 (24.8) | <0.001 | Chronic kidney
disease | 595 (9.6) | 393 (4.9) | <0.001 | Cerebrovascular
disease | 717 (11.6) | 607 (7.5) | <0.001 | Coronary artery
disease | 1623 (26.3) | 1164 (14.4) | <0.001 | | Systolic blood pressure | 121 ± 15 | 133 ± 15 | <0.001 | | Diastolic blood pressure | 61 ± 6 | 79 ± 7 | <0.001 | | Pulse pressure | 59 ± 14 | 54 ± 14 | <0.001 | | Number of antihypertensives | 1.2 ± 1.2 | 1.0 ± 1.1 | <0.001 | | Number of antihypertensives | | | <0.001 | | 0 | 2182 (35.3) | 3483 (43) | | | 1 | 1697 (27.5) | 2228 (27.5) | | | 2 | 1409 (22.8) | 1598 (19.7) | | | 3 | 684 (11.1) | 606 (7.5) | | | 4 | 169 (2.7) | 156 (1.9) | | | 5 | 31 (0.5) | 22 (0.3) | | | 6 | 3 (0) | 2 (0) | | | Medications by class | | | | | Beta blocker | 1732 (28) | 1828 (22.6) | <0.001 | | Alpha blocker | 1110 (18) | 885 (10.9) | <0.001 | | ACE-I/ARB | 2531 (47.1) | 2569 (36) | <0.001 | Calcium channel
blocker | 1032 (16.7) | 957 (11.8) | <0.001 | | Thiazide diuretic | 1402 (22.7) | 2000 (24.7) | 0.006 | | Loop diuretic | 635 (10.3) | 358 (4.4) | <0.001 | | All-cause mortality | 617 (10) | 399 (4.9) | <0.001 |
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DBP: diastolic blood pressure; ACE-I: angiotensin converting enzyme inhibitors; ARB: angiotensin receptor blockers.
Values reported as (%) or means ± SD.
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