Effects of continuous positive airway pressure therapy on resistant hypertension.
|Study||Study design, population||Sample size ()||Intervention||Results|
Logan et al., 2003 ||Prospective observational, refractory HTN, AHI ≥ 10||11 ||CPAP for 2 nights in sleep lab and then 2 months ||CPAP used BP acutely and over two months|
Martinez -Garcia et al., 2007 ||Prospective observational, difficult to treat HTN, AHI ≥ 15||33 ||CPAP for 2 months ||CPAP systolic BP, particularly at night|
Dernaika et al., 2009 ||Retrospective chart review, observational, HTN, AHI > 5||98||CPAP therapy for 1 year, controlled HTN ( 56) versus resistant HTN |
|CPAP permitted deescalation of anti-HTN treatment in 71% of subjects with resistant HTN, no significant change in controlled HTN|
Lozano et al., 2010 ||Prospective randomized controlled parallel trial, resistant HTN, AHI ≥ 15||75||CPAP ( 38) versus conventional treatment ( 37) ||CPAP for 3 months led to in 24 hr ABP in patients who used CPAP > 5.8 hr/night|
|24 hr ABP: 24-hour ambulatory blood pressure monitoring, AHI: apnea hypopnea index, BP: blood pressure, CPAP: continuous positive airway pressure, HTN: hypertension.|