International Journal of Hypertension / 2013 / Article / Tab 4

Research Article

Serum Cotinine Levels and Prehypertension in Never Smokers

Table 4

Association between serum cotinine levels and prehypertension by ethnicity.

Serum cotinine quartilesNo. at risk CasesAge-, sex-adjusted odds ratio
(95% CI)
Multivariable-adjusted odds ratio
(95% CI)*

Whites
 Quartile 1 (≤0.024 ng/mL)191671 (referent)1 (referent)
 Quartile 2 (0.025–0.054 ng/mL)205781.16 (0.76, 1.78)1.17 (0.76, 1.81)
 Quartile 3 (0.055–0.223 ng/mL)195871.62 (1.03, 2.54)1.49 (0.94, 2.37)
 Quartile 4 (≥0.224 ng/mL)182731.38 (0.80, 2.37)1.31 (0.75, 2.28)
P-trend0.12670.2190
Non-Whites
 Quartile 1 (≤0.024 ng/mL)297981 (referent)1 (referent)
 Quartile 2 (0.025–0.054 ng/mL)3191101.21 (0.82, 1.78)1.22 (0.85, 1.75)
 Quartile 3 (0.055–0.223 ng/mL)313981.15 (0.83, 1.61)1.12 (0.79, 1.59)
 Quartile 4 (≥0.224 ng/mL)3251231.81 (1.27, 2.60)1.76 (1.21, 2.56)
P trend0.00430.0095

*Adjusted for age (years), sex (men, women), education categories (<high school, high school, >high school), drinking (never drinker, former drinker, 1 or 2 drink/day, ≥3 drinks/day), BMI (normal weight, overweight, obese), glycohemoglobin (%), total cholesterol (mg/dL), below poverty level (%), and hormone use (ever, never).
P interaction of cotinine quartiles and Whites = 0.5509.