Mapping Metabolic Brain Activity in Three Models of Hepatic Encephalopathy

Table 1

Metabolic activity of the selected brain regions in the studied groups.

	PH	HA	TAA
Prefrontal cortex
PL	18.364 ± 0.460^a,b	26.781 ± 1.032	22.591 ± 0.379^a
IL	18.470 ± 0.504^a	26.988 ± 0.916	19.432 ± 0.401^a
Ventral Striatum
AcC	21.362 ± 0.395^a,b	31.812 ± 1.032	25.552 ± 0.498^a
AcS	22.210 ± 0.748^a,b	36.940 ± 1.227	32.409 ± 0.715^a
Thalamic nuclei
ADT	30.525 ± 0.736^a,b	50.930 ± 2.024	40.025 ± 1.302^a
AVT	24.717 ± 0.525^a	31.753 ± 1.412	27.631 ± 1.120^a
MDT	19.307 ± 0.879^a	27.361 ± 0.809	18.242 ± 0.921^a
Hippocampus
DG	23.413 ± 0.500^a,b	39.550 ± 1.75	32.663 ± 1.739^a
CA3	16.318 ± 0.488^a,b	22.633 ± 0.763	12.592 ± 0.568^a
CA1	18.128 ± 0.707^a	24.820 ± 0.915	18.250 ± 0.915^a
Mammillary nuclei
mMM	22.949 ± 1.151	23.490 ± 1.336	23.769 ± 1.479
lMM	17.643 ± 0.950	16.792 ± 0.633	15.777 ± 0.597
LM	25.923 ± 1.113	26.624 ± 1.246	26.665 ± 0.489

Values are mean ± SEM.
PH: portal hypertension, HA: hyperammonemia, TAA: thioacetamide.
^a𝑃<0.05 statistically significant value in relation to HA.
^b𝑃<0.05 statistically significant value in relation to TAA.