Clinical Implications of the Change in Glomerular Filtration Rate with Adrenergic Blockers in Patients with Morning Hypertension: The Japan Morning Surge-1 Study

Table 4

Factors associated with change in eGFR.

Variable	Change in UACR (6th month minus baseline)
	Added treatment group (𝑛=308)		Control group (𝑛=303)
	β coefficient	𝑃 value	β coefficient	𝑃 value
Change in eGFR (6th month minus baseline)	0.198	0.001	−0.002	0.966
Adjusted 𝑅^2	0.093		0.115

Adjustments were made for body mass index, hyperlipidemia (Yes = 1; No = 0), diabetes mellitus (Yes = 1; No = 0), smoking habit (Yes = 1; No = 0), drinking habit (Yes = 1; No = 0), change in morning systolic BP, eGFR at baseline, and the use of renin angiotensin system inhibitors.
UACR: urinary albumin to creatinine ratio. eGFR: estimated glomerular filtration rate. BP: blood pressure. 𝑅²: determination coefficient.