Review Article

Efficacy of Telmisartan Plus Amlodipine in Nonresponders to CCB Monotherapy

Table 1

Details of trials identified for inclusion into the analysis.

TrialDescriptionPatient numbersStudy duration (weeks)Run-in treatment (weeks)Randomized treatments (8 weeks)

NCT00558428
Neldam et al. 2011 [20]
A5 nonresponder trial (TEAMSTA-5) A5 (6)A5, A10, T40/A5, T80/A5
NCT00558064
Boehringer Ingelheim data on file [26]
T40/A5 in A5 nonresponder trial A5 (6)A5, T40/A5
NCT01103960
Boehringer Ingelheim data on file [27]
T80/A5 in A5 nonresponder trial A5 (6)A5, T80/A5
NCT00553267
Neldam et al. 2011 [25]
A10 nonresponder trial (TEAMSTA-10) A5 (2), A10 (6)A10, T40/A10, T80/A10

A5: amlodipine 5 mg; A10: amlodipine 10 mg; T40: telmisartan 40 mg; T80: telmisartan 80 mg; TEAMSTA-5: telmisartan/amlodipine single-pill study to assess the efficacy in patients with essential hypertension not controlled on A5; TEAMSTA-10: telmisartan/amlodipine single-pill study to assess the efficacy in patients with essential hypertension not controlled on A10.