Review Article

Efficacy of Telmisartan Plus Amlodipine in Nonresponders to CCB Monotherapy

Table 3

OR for goal attainment and response rates in patients not at goal with A5 monotherapy.

Goal or response target (mm Hg)A10 versus A5
OR (95% CI)
T40/A5 versus A5
OR (95% CI)
T80/A5 versus A5
OR (95% CI)

BP < 140/90 2.13 (1.49, 3.05)3.07 (2.34, 4.04)3.43 (2.54, 4.64)
DBP < 902.24 (1.58, 3.19)2.62 (2.00, 3.44)3.00 (2.22, 4.07)
DBP < 90 or reduction 10 2.12 (1.53, 2.96)2.71 (2.10, 3.51)2.73 (2.05, 3.65)
SBP < 140 1.94 (1.35, 2.81)2.99 (2.24, 4.00)3.25 (2.37, 4.48)
SBP < 140 or reduction 20 1.90 (1.36, 2.68)2.69 (2.06, 3.52)2.86 (2.11, 3.90)

A5: amlodipine 5 mg; A10: amlodipine 10 mg; BP: blood pressure; CI: confidence interval; DBP: diastolic blood pressure; OR: odds ratio; SBP: systolic blood pressure; T40: telmisartan 40 mg; T80: telmisartan 80 mg.