Research Article

Relationship between Plasma Aldosterone Levels and Left Ventricular Mass in Hypertensive Africans

Table 2

Biochemical, hormonal, and echocardiographic characteristics of the subjects.

Variable Hypertensives Normal controls value
( ) ( )

Plasma  sodium (mmol·L−1) 136.44 (7.874) 139.58 (6.591) 0.0328
Plasma  potassium (mmol·L−1) 4.02 (0.801) 4.11 (0.775) 0.5814
Urinary  sodium (mmol·L−1) 68.35 (41.173) 63.33 (40.538) 0.4968
Urinary  potassium (mmol·L−1) 16.06 (10.544) 13.99 (10.782) 0.2036
Urinary  sodium excretion (mmol·24 hr−1) 103.93 (63.571) 90.77 (50.873) 0.4522
Urinary  potassium excretion (mmol·24 hr−1) 24.04 (16.527) 20.44 (14.761) 0.1863
Plasma  renin (ng·mL−1) 21.03 (6.974) 24.66 (7.592) 0.0013
Plasma  aldosterone (nmol·L−1) 245.82 (59.498) 262.46 (58.136) 0.1162
ARR 12.66 (5.112) 11.03 (2.657) 0.1198
Left  atrial  diameter (cm) 3.94 (0.511) 3.69 (0.491) 0.0070
Aortic  valve  opening (cm) 1.89 (0.257) 1.86 (0.243) 0.4785
LV  posterior  wall thickness (cm) 1.19 (0.193) 1.05 (0.111) 0.0000
IV  septal  thickness (cm) 1.11 (0.224) 0.97 (0.125) 0.0000
LV  mean  wall thickness (cm) 1.15 (0.186) 0.99 (0.085) 0.0000
LV mass  index (g·m−2.7) 52.56 (14.483) 42.02 (8.315) 0.0000
Relative  wall thickness 0.5 (0.091) 0.46 (0.071) 0.0264
LV geometry
 Normal  geometry (%) 15.9 42.0
 Concentric remodelling (%) 43.9 50.0 0.0000
 Eccentric hypertrophy (%) 12.2 8.0
 Concentric hypertrophy (%) 28.0 0

ARR: aldosterone-to-renin ratio; LV: left ventricular; IV: interventricular.