Nox2 Deficiency Prevents Hypertension-Induced Vascular Dysfunction and Hypertrophy in Cerebral Arterioles

Figure 3

Graph showing endothelium-dependent and -independent vasodilation in cerebral arterioles. Acetylcholine (Ach, 10⁻⁵ mol/L) (a) or sodium nitroprusside (SNP, 10⁻⁷ mol/L) (b) was suffused in artificial CSF for 5 min in 8 mice.  ^∗𝑃<0.05 versus left-sided WT group; ^†𝑃<0.05 versus right-sided WT group; and ^‡𝑃<0.05 versus right-sided Nox2-/y group.

(a)

(b)