Antioxidant Treatment Reverts Increased Arterial Basal Tone and Oxidative Stress in Nephrectomized (5/6) Hypertensive Rats

<table>Effect of tempol 10<sup>−5</sup> M on NO levels (a) Typical experiment of direct measurement of NO in unrubbed aortic rings from SR (upper), NefR (middle), and NefR-T (lower) and the effect of tempol (arrows). (b) Average of effect of tempol on direct measurement of NO in unrubbed aortic rings of SR (white bars), NefR (black bars), and NefR-T (gray bars). **<svg height="11.375" id="M130" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> NefR-T versus SR; ***<svg height="11.375" id="M131" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 66.875 11.375" width="66.875" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> NefR versus SR; <sup>+++</sup><svg height="11.375" id="M132" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 66.875 11.375" width="66.875" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> tempol versus basal. Two way ANOVA. Data are expressed as mean ± standard error. The number of rings is given in parentheses.</table>

International Journal of Hypertension

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Figure 3

Figure 3: Antioxidant Treatment Reverts Increased Arterial Basal Tone and Oxidative Stress in Nephrectomized (5/6) Hypertensive Rats 