Statin Improves Flow-Mediated Vasodilation in Chronic Kidney Diseases

Table 1

Data on study patients.

	Baseline	Caduet
Age (y)	65±2
Sex (male: %)	52
Diabetes (%)	31
Serum creatinine (mg/dL)	1.43±0.07	1.44±0.08
Urinary protein (g/gCr)	0.99±0.12	0.96±0.11
Blood pressure (mmHg)	133±2/74±1	135±2/74±1
Pulse rate (bpm)	75±2	74±2
Total cholesterol (mg/dL)	196±3	187±2^∗
Triglycerides (mg/dL)	138±8	131±7^∗
HDL-C (mg/dL)	52±2	55±2^∗
High sensitive CRP (mg/L)	1.2±0.1	1.1±0.1
Central blood pressure (mmHg)	124±3	122±3
Flow-mediated dilation (%)	2.3±0.2	2.7±0.2^∗
Medications
Angiotensin receptor blockers	17 patients
Direct renin inhibitors	12 patients
Converting enzyme inhibitor	4 patients
Diuretics	20 patients
Beta blockers	8 patients
Alpha blockers	7 patients
CNS-acting antihypertensives	3 patients

Cr: creatinine; bpm: beats per minute; CRP: C-reactive protein; and HDL-C: high density lipoprotein cholesterol. *Indicates significant difference from respective baseline value.