Salusins: Potential Use as a Biomarker for Atherosclerotic Cardiovascular Diseases

Table 1

Atherogenic effects of salusins on human vascular cells.

	Salusin-𝛼	Salusin-𝛽	Reference
EC
IL-1𝛽 expression	→	↑	[36]
MCP-1 expression	→	↑	[36]
ICAM-1 expression	→	↑	[36]
VCAM-1 expression	→	↑	[36]
Monocyte
Adhesion to EC	→	↑	[36]
Macrophage
Foam cell formation	↓	↑	[37]
ACAT1 expression	↓	↑	[37]
SR-A expression	→	→	[37]
ABCA1 expression	→	→	[37]
VSMC
Proliferation	↗	↑	[17]
Fibroblast
Proliferation	↗	↑	[17]

Arrows indicate the stimulatory (↑, ↗), suppressive (↓), or negative (→) effects listed in the right column.