The Flavin-Containing Monooxygenase 3 Gene and Essential Hypertension: The Joint Effect of Polymorphism E158K and Cigarette Smoking on Disease Susceptibility

Table 3

The FMO3 genotype cigarette smoking interaction and susceptibility to essential hypertension in Kursk population.

FMO3; genotype	EH patients; (%)		Controls; (%)		OR (95% CI)
	Smokers ()	Nonsmokers; ()	Smokers ()	Nonsmokers; ()	Smokers	Nonsmokers
158KK	198 (23.5)	93 (22.9)	88 (18.2)	57 (19.2)	1.38; (1.04–1.83)*	1.25; (0.83–1.81)

*Means a statistically significant association () after adjustment for multiple tests ( = 0.046).