Time-Related Alteration in Flow- (Shear Stress-) Mediated Remodeling in Resistance Arteries from Spontaneously Hypertensive Rats

Figure 3

Phenylephrine- (1 μmol/L, (a)) and KCl (80 mmol/L, (b)) evoked contraction measured in mesenteric resistance arteries isolated from WKY rats and SHRs submitted to low flow (LF), high flow (HF), or normal flow (NF) for 1, 3, 8, or 24 weeks. Values represent mean ± SEM (𝑛=12 rats per group). ^∗𝑃<0.01, HF or LF versus NF arteries. ^#𝑃<0.05, SHRs versus WKY rats, within equivalent arteries (NF, LF, or HF).

(a)

(b)