Time-Related Alteration in Flow- (Shear Stress-) Mediated Remodeling in Resistance Arteries from Spontaneously Hypertensive Rats

Table 1

Blood flow (µL/min), measured using a Transonic probe in NF, LF, and HF arteries of WKY rats and of SHRs.

Time after surgery	1 week	3 weeks	2 months	6 months
NF artery WKY rats	345 ± 33	354 ± 40	378 ± 46	402 ± 38
LF artery WKY rats	110 ± 21*	123 ± 23*	90 ± 21*	54 ± 16∗$
HF artery WKY rats	673 ± 52*	661 ± 64*	695 ± 70*	724 ± 79*
NF artery SHRs	326 ± 38	332 ± 41	367 ± 45	350 ± 37
LF artery SHRs	93 ± 18*	103 ± 24*	77 ± 18*	50 ± 14∗$
HF artery SHRs	654 ± 45*	598 ± 42*	645 ± 69*	688 ± 70*

Mean ± SEM is presented (𝑛=6 per group in the WKY rats and 𝑛=5 per group in the SHRs).
* 𝑃<0.05, HF or LF versus NF arteries.
^$𝑃<0.05, 3 weeks, 2 months, or 6 months versus 1 week.