International Journal of Hypertension / 2014 / Article / Tab 7

Research Article

Quantifying Proteinuria in Hypertensive Disorders of Pregnancy

Table 7

Reported cutoff values for UPCR and diagnostic summary in pregnant women with hypertensive disorders.

StudyUPCRProtein estimation methodSensitivity (%)Specificity (%)Area under receiver operating curve (95% CI)Positive likelihood ratioNegative likelihood ratio

Rodriguez-Thompson and Lieberman 2001 [12]0.19Pyrogallol red reaction90700.91 (0.87 to 0.96)30.14
Durnwald and Mercer 2003 [13]0.39Biuret method72.673.
Al et al. 2004 [14]0.19Trichloroacetic acid85730.86 (0.80 to 0.93)3.150.21
Yamasmit et al. 2004 [15]0.25Pyrogallol red reaction96.692.30.9312.550.04
Taherian et al. 2006 [16]0.18Trichloroacetic acid86.31000.94 (0.88 to 0.98)#0.14
Leaños-Miranda et al. 2007 [17]0.30Bradford method98.298.8*81.80.02
Wheeler et al. 2007 [18]0.21Biuret method86.877.60.823.880.17
Aggarwal et al. 2008 [10]1.14Biuret method7275*2.880.37
Shaikh et al. 2010 [19]0.20Biuret method91.287.80.847.470.10
Dwyer et al. 2008 [5]0.28Pyrogallol red reaction65950.83 (0.76–0.88)130.36
Kyle et al. 2008 [20]0.27Polyethylene glycol turbidimetry92.397.1*31.820.07
Eslamian et al. 2011 [21]0.22Turbidimetric method8792.60.93 (0.85–0.99)11.760.14
Kumari et al. 2013 [22]0.30Coomassie reagent method90840.835.650.12
Gaddy-Dubac et al. 2013 [23]0.30Not mentioned32.9850.74 (0.67–0.82)2.190.79
Sharma et al. 2013 [24]0.25Biuret method69750.79 (0.66–0.92)2.760.41
Park et al. 2013 [11]0.63Pyrogallol red reaction87.11000.956 (0.90–1.00)#0.13
Present study 20140.45Benzethonium method82.187.50.89 (0.83–0.95)6.560.21

not calculated in the study.
indicates very high values, but cannot be calculated because of empty cell in 2 × 2 table.

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