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International Journal of Hypertension
Volume 2015, Article ID 579497, 5 pages
Research Article

Micro and Macro Element Composition of Kalanchoe integra Leaves: An Adjuvant Treatment for Hypertension in Ghana

1Department of Pharmaceutical Chemistry, UGSOP, Legon, Ghana
2Department of Pharmacology and Toxicology, UGSOP, Legon, Ghana
3Geological Survey Department, Accra, Ghana

Received 25 June 2015; Revised 25 August 2015; Accepted 14 September 2015

Academic Editor: Guang-Hui Dong

Copyright © 2015 S. Frimpong-Manso et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Two samples, water extract and blended whole leaves, of fresh Kalanchoe integra leaves (Crassulaceae), a traditional antihypertensive medicine used in Ghana, were analyzed with Energy Dispersive X-Ray Fluorescence spectroscopy (EDXRF). Analysis revealed 12 macro and 26 micro elements in both extracts. Further quantitative assessment of the results for amounts of elements that are pharmacologically significant revealed that the amounts of calcium, potassium, and magnesium present in the extracts could be correlated to its traditional usage in managing hypertension and arrhythmias. However, heavy metals (lead and inorganic arsenic) detected in the extracts may pose a threat at doses normally used traditionally for the treatment of hypertension.