Research Article

Preeclampsia Is Associated with Increased Central Aortic Pressure, Elastic Arteries Stiffness and Wave Reflections, and Resting and Recruitable Endothelial Dysfunction

Table 3

VRT-related changes in vascular parameters of the study groups according to pregnancy status.

Healthy pregnant (HP) Gestational hypertension (GH) Preeclampsia (PE) value
MV ± SDMV ± SDMV ± SD

FMD (%)9.4 ± 3.03.6 ± 3.3a2.2 ± 2.9a<0.001
L-FMC (%)−7.8 ± 3.7−4.5 ± 2.1−0.7 ± 3.5a<0.001
ΔPWVcr (%)−13.9 ± 9.4−0.9 ± 6.9a7.0 ± 8.5a<0.001
Peak shear rate (s−1)231.7 ± 72.6237.6 ± 67.5219.5 ± 59.50.86
ΔShear rate (%)113.8 ± 87.4131.2 ± 53.7168.6 ± 97.10.39

Values are expressed as mean value (MV) ± standard deviation (SD). Post hoc test with multiple comparisons: a indicate with respect to HP and GH, respectively. All comparisons were determined using ANOVA + Bonferroni test. HP: healthy pregnancies; GH: gestational hypertension; PE: preeclamptic pregnancies; FMD: flow-mediated dilation; L-FMC: low-flow-mediated constriction; PWVcr: carotid-to-radial pulse wave velocity. Between groups.