International Journal of Hypertension / 2016 / Article / Tab 2

Research Article

The Hypertension of Hemophilia Is Not Explained by the Usual Cardiovascular Risk Factors: Results of a Cohort Study

Table 2

Comparison of untreated (not taking antihypertensive medications) PWH and NHANES subjects.
(a)

VariableNHANESPWH
Median (IQR)Median (IQR)

Systolic BP (mmHg)118 (112–125)1710125 (118–134)342<0.001
Diastolic BP (mmHg)72 (64–78)171078 (73–83)342<0.001
BMI (kg/m2)26.9 (23.7–30.5)170326.1 (22.9–29.3)3230.016
Creatinine (mg/dL)0.92 (0.82–1.02)16130.90 (0.75–1.00)326<0.001
eGFR (mL/min/1.73 m2)107 (94–119)1613112 (100–124)326<0.001
Cholesterol (total) (mg/dL)188 (162–217)1618170 (146–196)205<0.001

(b)

VariableNHANESPWH
(%) (%)

HIVPositive7 (0.5)66 (20.5)<0.001
Negative1464 (99.5)256 (79.5)
HCVPositive30 (1.9)208 (63.8)<0.001
Negative1590 (98.2)118 (36.2)
DiabetesPositive100 (5.9)5 (1.5)0.001
Negative1610 (94.2)336 (98.5)
SmokingCurrent473 (30.8)42 (18.1)<0.001
Former300 (19.5)37 (16.0)
Never765 (49.7)153 (66.0)

NHANES indicates subjects from the National Health and Nutrition Examination Survey of the general United States population; PWH, patients with hemophilia; IQR, interquartile range; BP, blood pressure; BMI, body mass index; eGFR, estimated glomerular filtration rate; and HCV, hepatitis C virus.