International Journal of Hypertension / 2016 / Article / Tab 4

Research Article

The Hypertension of Hemophilia Is Not Explained by the Usual Cardiovascular Risk Factors: Results of a Cohort Study

Table 4

Analyses of covariance comparing log SBP values of untreated (not taking antihypertensive medications) PWH and NHANES subjects after adjusting for age and each covariate.

Covariate Regression coefficient for (PWH versus NHANES)
95% CI

Young adults (18–29 years)
 No covariates (age  +   only)0.0690.050, 0.088<0.0010.085
 log BMI0.0730.058, 0.088<0.0010.177
 log (1 + Creatinine)0.0680.052, 0.084<0.0010.110
 eGFR0.0680.052, 0.084<0.0010.110
 log TotalCholesterol0.0790.060, 0.098<0.0010.094
 Smoking status0.0710.052, 0.089<0.0010.087
 HCV0.0660.048, 0.085<0.0010.104
 Race0.0680.053, 0.083<0.0010.101
 All covariates0.0810.057, 0.105<0.0010.159

Older adults (30–79 years)
 No covariates (age  +   only)0.0310.013, 0.049<0.0010.041
 log BMI0.0460.030, 0.061<0.0010.087
 log (1 + Creatinine)0.0380.022, 0.054<0.0010.052
 eGFR0.0370.020, 0.053<0.0010.052
 log TotalCholesterol0.0360.017, 0.056<0.0010.060
 Smoking status0.0350.017, 0.052<0.0010.043
 HCV0.012−0.015, 0.0390.3840.051
 Race0.0380.022, 0.053<0.0010.055
 All covariates0.005−0.027, 0.0360.7690.121
 All covariates except HCV0.0490.029, 0.069<0.0010.111

indicates the binary variable that distinguishes PWH from NHANES ( for PWH, for NHANES); PWH, patients with hemophilia; NHANES, subjects from the National Health and Nutrition Examination Survey of the general United States population; , regression coefficient for representing change in log SBP per unit increase of the selected covariate; CI, confidence interval; , square of the multiple correlation coefficient; BMI, body mass index; eGFR, estimated glomerular filtration rate; HCV, hepatitis C virus.
Age, log BMI, eGFR, log TotalCholesterol, smoking status, HCV, and race.