International Journal of Hypertension / 2016 / Article / Tab 5

Research Article

The Hypertension of Hemophilia Is Not Explained by the Usual Cardiovascular Risk Factors: Results of a Cohort Study

Table 5

Analyses of covariance comparing log SBP values of treated (taking antihypertensive medications) PWH and NHANES subjects after adjusting for age and each covariate.

Covariate Regression coefficient for (PWH versus NHANES)
95% CI

Older adults (30–79 years)
 No covariates (age  +   only)0.0470.017, 0.0780.0030.020
 log BMI0.0380.011, 0.0650.0060.022
 log (1 + Creatinine)0.0450.019, 0.072<0.0010.025
 eGFR0.0440.018, 0.0700.0010.023
 log TotalCholesterol0.0640.033, 0.095<0.0010.050
 Diabetes0.0420.016, 0.0680.0010.024
 Smoking status0.0420.012, 0.0720.0060.027
 HCV0.0460.002, 0.0900.0390.023
 Race0.0410.015, 0.0660.0020.041
 All covariates0.0530.001, 0.1040.0450.087

indicates the binary variable that distinguishes PWH from NHANES ( for PWH, for NHANES); PWH, patients with hemophilia; NHANES, subjects from the National Health and Nutrition Examination Survey of the general United States population; , regression coefficient for representing change in log SBP per unit increase of the selected covariate; CI, confidence interval; , square of the multiple correlation coefficient; BMI, body mass index; eGFR, estimated glomerular filtration rate; HCV, hepatitis C virus.
Age, log BMI, eGFR, log TotalCholesterol, diabetes, smoking status, HCV, and race.