Excess of Aminopeptidase A in the Brain Elevates Blood Pressure via the Angiotensin II Type 1 and Bradykinin B2 Receptors without Dipsogenic Effect

<div>Representative traces of arterial pressure after intracerebroventricular (icv) administration of aminopeptidase A (APA). Wistar-Kyoto rats received icv administration of vehicle or APA in a conscious, unrestrained state. Icv of APA rapidly increased blood pressure. Then, blood pressure gradually decreased. The duration of pressor response was prolonged in a dose-dependent manner. Arrow: time for drug administration.</div>

International Journal of Hypertension

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Figure 2

Figure 2: Excess of Aminopeptidase A in the Brain Elevates Blood Pressure via the Angiotensin II Type 1 and Bradykinin B2 Receptors without Dipsogenic Effect 

Figure 2 | Excess of Aminopeptidase A in the Brain Elevates Blood Pressure via the Angiotensin II Type 1 and Bradykinin B2 Receptors without Dipsogenic Effect 