A Randomized, Double-Blind, Placebo-Controlled, Multicentre Trial of the Effects of a Shrimp Protein Hydrolysate on Blood Pressure
Table 5
Results from Exploratory Analyses for Participants in the RPC Group.
Oxidized LDL (U/L)
ACE (ng/mL)
Renin (pg/mL)
Angiotensin I (pg/mL)
Angiotensin II (pg/mL)
Aldosterone (pg/mL)
W 0
Mean ± SD
111.4 ± 27.8
151 ± 59
645 ± 340
1,343 ± 850
0.309 ± 0.148
375 ± 142
Median (Min – Max)
116.6 (43.4 – 150.2)
142 (51 – 337)
584 (84 – 2,007)
1,045 (29 – 4,311)
0.275 (0.197 – 0.953)
364 (103 – 726)
W 8
Mean ± SD
110.9 ± 21.2
138 ± 46
640 ± 382
1,383 ± 1,134
0.283 ± 0.148
366 ± 128
Median (Min – Max)
113 (52.3 – 141.8)
130 (55 – 289)
589 (201 – 2,679)
1,042 (42 – 6,155)
0.217 (0.186 – 0.968)
370 (105 – 722)
Change from W 0 to W 8
Mean ± SD
-1 ± 33
-12 ± 54
-5 ± 327
39 ± 796
-0.026 ± 0.060
-9 ± 108
Median (Min – Max)
-6 (-64 – 95)
-5 (-141 – 89)
-26 (-1,201 – 1,203)
-2 (-2,738 – 3,428)
-0.01 (-0.176 – 0.101)
-8 (-264 – 393)
P-value
p=0.594
p=0.176
p=0.895
p=0.532
p<0.001
p=0.596
ACE: angiotensin converting enzyme; LDL: low-density lipoprotein; Max: maximum; Min: minimum; mL: milliliter; ng: nanogram; pg: picogram; SD: standard deviation; U/L: International units per liter; W: week. Within-group comparisons were made using the paired Student t-test. Logarithmic transformation required to achieve normality. Squared transformation required to achieve normality. Square root transformation required to achieve normality. Probability values P≤0.05 are statistically significant.
