Research Article

Prescribing Patterns of Antihypertensives for Treatment-Naïve Patients in South Korea: From Korean NHISS Claim Data

Table 4

Prescription pattern by the drug classes, either included in monotherapy or combination therapy, n (%).

ARBACEIBETACCBDiuretics

Overall150,6561 (51.61)90,784 (3.11)539,372 (18.48)1,314,597 (45.03)496,634 (17.01)
Age (mean ± SD)53.01 ± 12.7453.4 ± 17.7451.43 ± 16.1754.32 ± 13.7354.07 ± 13.81
 <206,928 (15.32)5,564 (12.30)15,015 (33.20)7,479 (16.54)3,092 (6.84)
 20–2931,458 (32.94)2,561 (2.68)35,064 (36.72)32,134 (33.65)13,038 (13.65)
 30–39156,422 (51.54)7,447 (2.45)66,968 (22.06)130,704 (43.06)48,151 (15.86)
 40–49415,900 (58.29)17,660 (2.48)118,228 (16.57)315,763 (44.25)124,418 (17.44)
 50–59476,338 (54.98)24,123 (2.78)142,677 (16.47)393,807 (45.45)148,443 (17.13)
 60–69251,389 (49.42)17,004 (3.34)87,818 (17.26)241,238 (47.43)86,640 (17.03)
 70–79131,138 (44.49)11,737 (3.98)55,469 (18.82)145,191 (49.26)54,624 (18.53)
 ≥8036,988 (40.38)4,688 (5.12)18,133 (19.80)48,281 (52.71)18,228 (19.90)
Sex
 Male904,778 (55.38)60,192 (3.68)275,763 (16.88)775,090 (47.44)251,286 (15.38)
 Female601,783 (46.82)30,592 (2.38)263,609 (20.51)539,507 (41.97)245,348 (19.09)
Income
Medical aid46,315 (41.27)3,943 (3.51)27,160 (24.20)46,751 (41.66)19,055 (16.98)
 Q1 (low)398,887 (52.05)22,550 (2.94)139,374 (18.19)353,498 (46.13)138,079 (18.02)
 Q2363,159 (52.13)20,640 (2.96)126,485 (18.16)315,653 (45.31)121,217 (17.40)
 Q3346,565 (52.23)21,268 (3.21)119,086 (17.95)299,447 (45.13)111,549 (16.81)
 Q4 (high)351,635 (51.68)22,383 (3.29)127,267 (18.7)299,248 (43.98)106,734 (15.69)
Residence
 Metropolitan909,496 (52.23)53,311 (3.06)320,725 (18.42)778,121 (44.69)282,095 (16.20)
 City430,908 (51.68)25,320 (3.04)156,480 (18.77)375,042 (44.98)148,404 (17.80)
 Rural166,157 (48.29)12,153 (3.53)62,167 (18.07)161,434 (46.92)66,135 (19.22)
Charlson comorbidity index
 0502,861 (53.60)12,245 (1.31)137,490 (14.66)456,193 (48.63)163,131 (17.39)
 1411,171 (51.96)18,536 (2.34)136,449 (17.24)355,466 (44.92)138,614 (17.52)
 2252,680 (50.79)19,096 (3.84)97,293 (19.56)212,683 (42.75)85,095 (17.10)
 ≥3339,849 (49.10)40,907 (5.91)168,140 (24.29)290,255 (41.94)109,794 (15.86)
Comorbidity
 Diabetes240,501 (64.74)21,283 (5.73)53,265 (14.34)127,538 (34.33)55,124 (14.84)
 Dyslipidemia465,523 (57.74)44,577 (5.53)155,768 (19.32)331,832 (41.16)124,074 (15.39)
 Congestive heart failure45,540 (37.71)22,783 (18.87)65,416 (54.18)37,246 (30.85)16,936 (14.03)
 Ischemic heart failure148,348 (36.94)40,612 (10.11)161,776 (40.29)178,876 (44.55)44,121 (10.99)
 Stroke67,621 (49.88)6,568 (4.84)34,636 (25.55)66,925 (49.37)19,360 (14.28)
 Chronic kidney disease16,310 (59.82)2,274 (8.34)5,974 (21.91)12,220 (44.82)3,257 (11.95)
 Cancer13,353 (29.92)1,531 (3.43)11,312 (25.35)24,520 (54.95)4,385 (9.83)
Provider type
 General hospital350,910 (37.95)67,357 (7.29)316,088 (34.19)406,074 (43.92)81,064 (8.77)
 Hospital161,403 (48.77)5,958 (1.80)57,090 (17.25)176,623 (53.37)55,586 (16.80)
 Clinic946,054 (60.62)14,843 (0.95)160,542 (10.29)668,985 (42.86)339,547 (21.76)
 Others48,194 (46.82)2,626 (2.55)5,652 (5.49)62,915 (61.12)20,437 (19.85)
Year
 2011312,074 (49.75)21,853 (3.48)115,374 (18.39)291,626 (46.49)132,317 (21.09)
 2012306,353 (51.24)20,206 (3.38)112,748 (18.86)257,977 (43.15)117,653 (19.68)
 2013300,076 (51.87)18,703 (3.23)104,476 (18.06)252,941 (43.73)94,175 (16.28)
 2014280,036 (52.01)15,514 (2.88)101,408 (18.83)245,769 (45.64)76,045 (14.12)
 2015308,022 (53.38)14,508 (2.51)105,366 (18.26)266,284 (46.15)76,444 (13.25)