Contribution of Four Polymorphisms in Renin-Angiotensin-Aldosterone-Related Genes to Hypertension in a Thai Population

Table 3

Effect allele frequencies of selected SNPs across different populations.

	Effect allele frequency
	Genome browser Ensembl
	Thais (EGAT study)	East Asian	South Asian	European	American	African	African American	European American	Aggregated populations
rs699	0.15	0.15	0.36	0.59	0.37	0.10	—	—	—
rs5186	0.06	—	—	—	—	—	0.06	0.29	—
rs1799998	0.3	0.29	0.45	0.49	—	0.18	—	—	—
rs1799752	0.32	—	—	—	—	—	—	—	<0.01

1000 Genomes Project Phase 3: East Asian (EAS: CDX, CHB, CHS, JPT, KHV), South Asian (SAS: BEB, GIH, ITU, PJL, STU), European (EUR: CEU, FIN, GBR, IBS, TSI), American (AMR: CLM, MXL, PEL, PUR), and African (AFR: ACB, ASW, ESN, GWD, LWK, MSL, YRI). NHLBI Exome Sequencing Project allele frequencies. HapMap Project: East Asian (EAS: CHB, JPT), South Asian (SAS: GIH), European (EUR: TSI, CEU), and African (AFR: ASW, LWK, YRI). Aggregated populations from the Exome Aggregation Consortium (ExAC).