Research Article

The Additive Interaction between Body Mass Index and Hypertension Family History in Han and Yugur: The China National Health Survey (CNHS)

Table 3

Associations and interactions of BMI and FHH on hypertension in Han and Yugur people adjusted for behavioral risk factors in China.

Han (N=4195)Yugur (N=1596)
OR (95% CI)RERI (95% CI)AP (95% CI)SI (95% CI)OR (95% CI)RERI (95% CI)AP (95% CI)SI (95% CI)

Model overweight
FHH(-)
 Normal weight1.001.00
 Overweight2.77 (2.12, 3.61)3.15 (1.89, 5.25)
FHH(+)
 Normal weight3.54 (2.75, 4.57)2.96 (1.86, 4.71)
 Overweight7.91 (6.12, 10.23)2.60 (1.17, 4.03)0.33 (0.19, 0.47)1.60 (1.26, 2.05)5.74 (3.65, 9.03)0.63 (-1.22, 2.48)0.11 (-0.20, 0.42)1.15 (0.75, 1.77)
Model obesity
FHH(-)
 Normal weight1.001.00
 Obesity4.61 (3.05, 6.98)8.09 (4.44, 14.77)
FHH(+)
 Normal weight3.74 (2.87, 4.86)2.81 (1.77, 4.45)
 Obesity14.06 (9.76, 20.25)6.72 (2.10, 11.33)0.48 (0.28, 0.67)2.06 (1.36, 3.11)14.16 (8.61, 23.28)4.25 (-1.56, 10.06)0.30 (-0.04, 0.64)1.48 (0.87, 2.51)

Models were adjusted for age, gender, current residence, educational level, smoking status, alcohol consumption, and physical activity.
BMI: body mass index, FHH: family history of hypertension, RERI: the relative excess risk due to interaction, AP: the attributable proportion due to interaction, SI: the synergy index.
Interaction was present if the 95% CIs of RERI and AP did not include 0 and the 95% CIs of SI did not include 1.