Clinical Study

Association of Lactate Dehydrogenase with In-Hospital Mortality in Patients with Acute Aortic Dissection: A Retrospective Observational Study

Table 2

Univariate analysis for in-hospital mortality.

OR95 CI value

Age (years)1.00(0.99, 1.01)0.898
BMI (kg/m2)1.00(0.97, 1.03)0.825
SBP (mmHg)0.99(0.98, 0.99)<0.001
DBP (mmHg)0.98(0.97, 0.98)<0.001
WBC (×109/L)1.07(1.04, 1.11)<0.001
Hb (g/L)0.99(0.99, 1.00)0.003
ALT (μ/L)1.00(1.00, 1.00)<0.001
AST (μ/L)1.00(1.00, 1.00)<0.001
ALB (g/L)0.96(0.94, 0.99)0.005
Cr (μmol/L)1.00(1.00, 1.00)<0.001
Gender
 MaleRef
 Female1.02(0.74, 1.40)0.896
Hypertension
 NoRef
 Yes0.99(0.75, 1.30)0.920
Diabetes
 NoRef
 Yes0.97(0.50, 1.89)0.922
Smoking
 NoRef
 Yes0.74(0.56, 0.99)0.040
Stroke
 NoRef
 Yes1.64(0.92, 2.90)0.094
Atherosclerosis
 NoRef
 Yes1.17(0.76, 1.80)0.476
Symptom
 Chest painRef
 Back pain1.09(0.61, 1.97)0.764
 Abdominal pain0.49(0.27, 0.91)0.025
 Syncope2.87(1.14, 7.20)0.025
 Other0.74(0.48, 1.16)0.187
Type of AAD (Stanford)
 ARef
 B0.16(0.12, 0.22)<0.001
Management
 MedicalRef
 Endovascular0.02(0.01, 0.03)<0.001
 Surgical0.08(0.05, 0.11)<0.001
Lactate dehydrogenase (μ/L)
(per 100 increment)1.10(1.06, 1.14)<0.001

Abbreviations: CI, confidence interval; OR, odds ratio; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; WBC, white blood cell; Hb, hemoglobin; ALT, alanine transaminase; AST, aspartate aminotransferase; ALB, albumin; Cr, creatinine; AAD, acute aortic dissection.