Association of Lactate Dehydrogenase with In-Hospital Mortality in Patients with Acute Aortic Dissection: A Retrospective Observational Study

Table 5

Results of subgroup analysis and interaction analysis.

Characteristic	No.	OR (95% CI)	for interaction
Age (years)			0.851
<70	1408	1.10 (1.06, 1.14)
≥70	118	1.12 (0.93, 1.35)
BMI (kg/m^2)			0.476
<18.5	57	1.12 (0.97, 1.29)
≥18.5, <23	445	1.07 (1.02, 1.13)
≥23	1024	1.12 (1.07, 1.18)
SBP (mmHg)			0.291
Low (50.00–132.00)	493	1.12 (1.06, 1.19)
Middle (133.00–157.00)	510	1.10 (1.04, 1.17)
High (158.00–246.00)	523	1.05 (0.99, 1.11)
DBP (mmHg)			0.398
Low (26.00–73.00)	480	1.09 (1.04, 1.14)
Middle (74.00–88.00)	522	1.13 (1.05, 1.22)
High (89.00–157.00)	524	1.05 (0.98, 1.13)
WBC (×10^9/L)			0.593
Low (2.14–9.25)	509	1.07 (0.98, 1.17)
Middle (9.26–12.48)	508	1.12 (1.05, 1.21)
High (12.49–29.10)	509	1.08 (1.04, 1.13)
Hb (g/L)			0.496
Low (11.00–118.00)	508	1.07 (1.02, 1.11)
Middle (119.00–134.00)	497	1.23 (1.12, 1.35)
High (135.00–215.00)	521	1.09 (1.03, 1.14)
ALT (μ/L)			0.062
Low (3.00–15.50)	506	1.19 (0.99, 1.42)
Middle (15.60–28.70)	510	0.89 (0.72, 1.09)
High (28.80–6817.30)	510	1.11 (1.07, 1.15)
AST (μ/L)			0.969
Low (2.85–17.00)	503	1.09 (0.84, 1.43)
Middle (17.10–26.20)	512	1.11 (0.95, 1.29)
High (26.30–11216.00)	511	1.09 (1.05, 1.13)
ALB (g/L)			0.234
Low (16.10–33.50)	494	1.10 (1.05, 1.15)
Middle (33.60–37.80)	522	1.19 (1.06, 1.32)
High (37.90–53.80)	510	1.07 (1.02, 1.13)
Cr (μmol/L)			0.268
Low (5.00–71.10)	505	1.14 (1.02, 1.28)
Middle (71.20–97.90)	511	1.01 (0.90, 1.14)
High (98.00–1718.80)	510	1.08 (1.04, 1.13)
Gender			0.133
Male	1227	1.12 (1.07, 1.17)
Female	299	1.05 (0.98, 1.13)
Symptom			0.055
Chest pain	1166	1.08 (1.04, 1.12)
Back pain	69	1.11 (0.94, 1.30)
Abdominal pain	108	1.30 (1.05, 1.60)
Syncope	19	2.04 (0.79, 5.23)
Other	164	1.10 (0.98, 1.23)
Hypertension			0.308
No	469	1.13 (1.06, 1.19)
Yes	1057	1.08 (1.04, 1.13)
Diabetes			0.944
No	1468	1.10 (1.06, 1.14)
Yes	58	1.11 (0.90, 1.37)
Smoking			0.833
No	1044	1.10 (1.06, 1.14)
Yes	482	1.11 (1.03, 1.19)
Stroke			0.805
No	1465	1.10 (1.06, 1.14)
Yes	61	1.15 (0.85, 1.55)
Atherosclerosis			0.360
No	1393	1.10 (1.06, 1.14)
Yes	133	1.23 (0.94, 1.61)
Type of AAD (Stanford)			0.798
A	703	1.09 (1.04, 1.14)
B	823	1.08 (1.03, 1.13)
Management			0.284
Medical	412	1.19 (1.06, 1.34)
Endovascular	647	1.10 (1.03, 1.17)
Surgical	467	1.09 (1.03, 1.15)

Abbreviations: CI, confidence interval; OR, odds ratio; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; WBC, white blood cell; Hb, hemoglobin; ALT, alanine transaminase; AST, aspartate aminotransferase; ALB, albumin; Cr, creatinine; AAD, acute aortic dissection.