Research Article

Polymorphism of MTHFR C677T Gene and the Associations with the Severity of Essential Hypertension in Northern Chinese Population

Table 3

Distribution of methylenetetrahydrofolate reductase 677T genotypes based on Hcy levels.

Hcy (µmol/L)NGenotype frequency (n) (%)aχ2 value
CCCTTT

5–1017946 (25.70)106 (59.22)27 (15.08)99.81<0.001
10–1540990 (22.00)237 (57.95)82 (20.05)
≥1539757 (14.36)149 (37.53)191 (48.11)

aχ2trend = 64.77, . Hcy: homocysteine.